Developmental analysis of the Hba(th-J) mouse mutation: effects on mouse peri-implantation development and identification of two candidate genes.

doi:10.1006/dbio.1995.0020

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Article

Developmental analysis of the Hba(th-J) mouse mutation: effects on mouse peri-implantation development and identification of two candidate genes.

Developmental biology - 1 Nov 1995

Hendrey J, Lin D, Dziadek M

Abstract excerpt

The Hba(th-J) mouse mutation is a deletion on chromosome 11 that spans the alpha-globin complex and causes alpha-thalassemia in heterozygous animals and in utero death of embryos homozygous for the deletion. We hypothesised that one or more genes closely linked to the Hba locus are also deleted i...

Topics

Animals
Base Sequence
Blastocyst
Chromosome Mapping
Crosses, Genetic
DNA Primers
Embryonic and Fetal Development
Female
Fetal Death
Genes, Lethal
Genotype
Globins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Hemoglobin A

Heterozygote

Homozygote

Male

Mice

Mice, Inbred C57BL

Source

Open in PubMed

Identifiers

PMID: 7589805
DOI: 10.1006/dbio.1995.0020

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7589805-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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