Article
Developmental analysis of the Hba(th-J) mouse mutation: effects on mouse peri-implantation development and identification of two candidate genes.
Developmental biology - 1 Nov 1995
Hendrey J, Lin D, Dziadek M
Abstract excerpt
The Hba(th-J) mouse mutation is a deletion on chromosome 11 that spans the alpha-globin complex and causes alpha-thalassemia in heterozygous animals and in utero death of embryos homozygous for the deletion. We hypothesised that one or more genes closely linked to the Hba locus are also deleted in these mutant mice and that deletion of these additional genes is responsible for the embryo lethality. We have...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
