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Article

RNA templating of molecular assembly and covalent modification patterning in early molecular evolution and modern biosystems.

Journal of theoretical biology - 7 Sept 2011

Dunn Ian S

Abstract excerpt

The Direct RNA Template (DRT) hypothesis proposes that an early stage of genetic code evolution involved RNA molecules acting as stereochemical recognition templates for assembly of specific amino acids in sequence-ordered arrays, providing a framework for directed covalent peptide bond formation. It is hypothesized here that modern biological precedents may exist for RNA-based structural templating with...

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PMID: 21703277
DOI: 10.1016/j.jtbi.2011.06.009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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