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Article

The APOE Genotype in Idiopathic Normal Pressure Hydrocephalus.

PloS one - 1 Jan 2016

Yang Yi, Tullberg Mats, Mehlig Kirsten, Rosengren Annika, Torén Kjell, Zetterberg Henrik, Wikkelsö Carsten

Abstract excerpt

INTRODUCTION: Amyloid plaque has been reported in brain biopsies from patients with idiopathic normal-pressure hydrocephalus (iNPH) and proposed as a significant feature of the pathophysiology. Presence of the apolipoprotein E ε4 (APOE ε4) allele is associated with increased risk of Alzheimer's disease (AD). AIMS: To compare the distribution of APOE genotype in iNPH patients with an age-matched population-based...

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Identifiers

PMID: 27441602
DOI: 10.1371/journal.pone.0158985
PMCID: PMC4956274

Genes

APOE

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