Article
Redifferentiation of smooth muscle cells after coronary angioplasty determined via myosin heavy chain expression.
Circulation - 1 Jul 1997
Aikawa M, Sakomura Y, Ueda M, Kimura K, Manabe I, Ishiwata S, Komiyama N, Yamaguchi H, Yazaki Y, Nagai R
Abstract excerpt
BACKGROUND: The pathophysiology of phenotypic modulation of smooth muscle cells (SMCs) involved in restenosis after angioplasty is not well understood. Smooth muscle myosin heavy chain (SM MHC) isoforms (SM1 and SM2) are specific markers for SMC differentiation. In particular, SM2 is useful as a...
Topics
- Aged
- Aged, 80 and over
- Angioplasty, Balloon, Coronary
- Biomarkers
- Cell Differentiation
- Coronary Artery Disease
- Coronary Vessels
- Female
- Humans
- Immunohistochemistry
- Male
- Middle Aged
- Muscle, Smooth, Vascular
- Myosin Heavy Chains
- Phenotype
- Recurrence
- Up-Regulation