Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Phenotypic modulation of vascular smooth muscle cells: dissection of transcriptional regulatory mechanisms.

Annals of the New York Academy of Sciences - 1 Dec 2001

Nagai R, Suzuki T, Aizawa K, Miyamoto S, Amaki T, Kawai-Kowase K, Sekiguchi K I, Kurabayashi M

Abstract excerpt

The smooth muscle myosin heavy chain (MHC) gene and its isoforms are excellent molecular markers that reflect smooth muscle phenotypes. The SMemb/Nonmuscle Myosin Heavy Chain B (NMHC-B) is a distinct MHC gene expressed predominantly in phenotypically modulated SMCs (synthetic-type SMC). To dissect the molecular mechanisms governing phenotypic modulation of SMCs, we analyzed the transcriptional regulatory...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Kruppel-Like Transcription Factors
Share to MAP Kinase Signaling System

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Muscle, Smooth, Vascular

Share to Myosin Heavy Chains

Share to Rabbits

Share to Trans-Activators

Share to Transcriptional Activation

Share to Zinc Fingers

Source

Identifiers

PMID: 11795310
DOI: 10.1111/j.1749-6632.2001.tb03930.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Phenotypic modulation of vascular smooth muscle cells: dissection of transcriptional regulatory mechanisms.PMID 11795310Read ↗

Multiple repressor pathways contribute to phenotypic switching of vascular smooth muscle cells.Semantic proximity Read ↗

Homeobox protein Hex induces SMemb/nonmuscle myosin heavy chain-B gene expression through the cAMP-responsive element.Semantic proximity Read ↗

Molecular Determinants of Vascular Smooth Muscle Cell DiversitySemantic proximity Read ↗

Expressional regulation of smooth muscle cell-specific genes in association with phenotypic modulation.Semantic proximity Read ↗

Transcriptional regulation of vascular smooth muscle cell proliferation, differentiation and senescence: Novel targets for therapy.Semantic proximity Read ↗

Molecular control of vascular smooth muscle cell differentiation and phenotypic plasticity.Semantic proximity Read ↗

BTEB2, a Krüppel-like transcription factor, regulates expression of the SMemb/Nonmuscle myosin heavy chain B (SMemb/NMHC-B) gene.Semantic proximity Read ↗

Interferon regulatory factor 8 modulates phenotypic switching of smooth muscle cells by regulating the activity of myocardin.Semantic proximity Read ↗

Sp1-dependent activation of KLF4 is required for PDGF-BB-induced phenotypic modulation of smooth muscle.Semantic proximity Read ↗

Vascular injury activates the ELK1/SND1/SRF pathway to promote vascular smooth muscle cell proliferative phenotype and neointimal hyperplasia.Semantic proximity Read ↗

Mesoderm/mesenchyme homeobox gene l promotes vascular smooth muscle cell phenotypic modulation and vascular remodeling.Semantic proximity Read ↗

DeltaEF1 mediates TGF-beta signaling in vascular smooth muscle cell differentiation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.