Article
Heterogeneity in smooth muscle cell population accumulating in the neointimas and the media of poststenotic dilatation of the rabbit carotid artery.
Biochemical and biophysical research communications - 29 May 1992
Okamoto E, Imataka K, Fujii J, Kuro-o M, Nakahara K, Nishimura H, Yazaki Y, Nagai R
Abstract excerpt
Rabbit smooth muscles contain at least three types of myosin heavy chain (MHC) isoforms; SM1, SM2 and SMemb (NMHC-B), the expression of which is developmentally regulated. We have recently reported that smooth muscles with the embryonic phenotype accumulate in the neointimas produced by endothelial denudation or high-cholesterol feeding. In this study, we examined MHC isoform expression in the neointimas and the...
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