Article
Structural definition of the H-2Kd peptide-binding motif.
The Journal of biological chemistry - 14 Apr 2006
Mitaksov Vesselin, Fremont Daved H
Abstract excerpt
Classic major histocompatibility complex (MHC) proteins associate with antigen- and self-derived peptides in an allele-specific manner. Herein we present the crystal structure of the MHC class I protein H-2K(d) (K(d)) expressed by BALB/c mice in complex with an antigenic peptide derived from influenza A/PR/8/34 nucleoprotein (Flu, residues 147-155, TYQRTRALV). Analysis of our structure in conjunction with the...
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