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Article

Loss of anti-viral immunity by infection with a virus encoding a cross-reactive pathogenic epitope.

PLoS pathogens - 1 Jan 2012

Chen Alex T, Cornberg Markus, Gras Stephanie, Guillonneau Carole, Rossjohn Jamie, Trees Andrew, Emonet Sebastien, de la Torre Juan C, Welsh Raymond M, Selin Liisa K

Abstract excerpt

T cell cross-reactivity between different strains of the same virus, between different members of the same virus group, and even between unrelated viruses is a common occurrence. We questioned here how an intervening infection with a virus containing a sub-dominant cross-reactive T cell epitope would affect protective immunity to a previously encountered virus. Pichinde virus (PV) and lymphocytic choriomeningitis...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Epitopes, T-Lymphocyte

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Source

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Identifiers

PMID: 22536152
DOI: 10.1371/journal.ppat.1002633
PMCID: PMC3334890

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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