Article
Single-strand conformation polymorphism analysis using capillary electrophoresis.
Current protocols in human genetics - 1 May 2003
Larsen Lars Allan, Christiansen Michael, Vuust Jens, Andersen Paal Skytt
Abstract excerpt
Single-strand conformation polymorphism (SSCP) is one of the most frequently used mutation detection methods. This unit describes a method of SSCP with automated analysis by capillary electrophoresis in order to increase the capacity and throughput. A protocol is provided for sample preparation. For a medium throughput laboratory, a single capillary instrument, as described in this unit, may be quite sufficient....
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