Article
High throughput fluorescent CE-SSCP SNP genotyping.
Molecular psychiatry - 1 Jul 1999
Gonen D, Veenstra-VanderWeele J, Yang Z, Leventhal B, Cook E H
Abstract excerpt
Large numbers of single nucleotide polymorphisms (SNPs) are being identified by several laboratories for the purpose of developing dense genetic maps. Single-strand conformation polymorphism (SSCP) analysis has been widely used as a method for detecting novel sequence variations in PCR products. Differences in migration of single-stranded DNA can be used not only to find mutations, but to genotype SNPs in large...
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