Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Quantitative trait loci controlling halothane sensitivity in Caenorhabditis elegans.

Proceedings of the National Academy of Sciences of the United States of America - 22 Jul 1997

van Swinderen B, Shook D R, Ebert R H, Cherkasova V A, Johnson T E, Shmookler Reis R J, Crowder C M

Abstract excerpt

Genetic analysis is an essential tool for defining the molecular mechanisms whereby volatile anesthetics (VA) disrupt nervous system function. However, the degree of natural variation of the genetic determinants of VA sensitivity has not been determined nor have mutagenesis approaches been very s...

Topics

Anesthetics, Inhalation
Animals
Caenorhabditis elegans
Chromosome Mapping
Drug Resistance
Halothane
Male
Phenotype
Sexual Behavior, Animal

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 9223344
DOI: 10.1073/pnas.94.15.8232
PMCID: PMC21586

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9223344-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Quantitative trait loci controlling halothane sensitivity in Caenorhabditis elegans.PMID 9223344Read ↗

Common genetic determinants of halothane and isoflurane potencies in Caenorhabditis elegans.Semantic proximity Read ↗

The genetics of response to volatile anesthetics in Caenorhabditis elegans.Semantic proximity Read ↗

Mutations conferring new patterns of sensitivity to volatile anesthetics in Caenorhabditis elegans.Semantic proximity Read ↗

Interaction of GABA and volatile anesthetics in the nematode Caenorhabditis elegans.Semantic proximity Read ↗

Alternatives to mammalian pain models 1: use of C. elegans for the study of volatile anesthetics.Semantic proximity Read ↗

A neomorphic syntaxin mutation blocks volatile-anesthetic action in Caenorhabditis elegans.Semantic proximity Read ↗

Optical reversal of halothane-induced immobility in C. elegans.Semantic proximity Read ↗

A gain-of-function mutation in adenylate cyclase confers isoflurane resistance in Caenorhabditis elegans.Semantic proximity Read ↗

You Don't Always Get What You Want!Semantic proximity Read ↗

Natural variation suggests candidate genes underlying <i>Caenorhabditis elegans</i> susceptibility to diverse toxicantsSemantic proximity Read ↗

A genetic study of the anesthetic response: mutants of Drosophila melanogaster altered in sensitivity to halothane.Semantic proximity Read ↗

Natural variation suggests candidate genes underlying Caenorhabditis elegans susceptibility to diverse toxicants.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.