Common genetic determinants of halothane and isoflurane potencies in Caenorhabditis elegans.

doi:10.1097/00000542-199812000-00030

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Article

Common genetic determinants of halothane and isoflurane potencies in Caenorhabditis elegans.

Anesthesiology - 1 Dec 1998

van Swinderen B, Galifianakis A, Crowder M

Abstract excerpt

BACKGROUND: Genetics provides a way to evaluate anesthetic action simultaneously at the molecular and behavioral levels. Results from strains that differ in anesthetic sensitivity have been mixed in their support of unitary theories of anesthesia. Here the authors use the previously demonstrated...

Topics

Anesthetics, Inhalation
Animals
Behavior, Animal
Caenorhabditis elegans
Chromosome Mapping
Dose-Response Relationship, Drug
Ethanol
Halothane
Isoflurane
Phenotype

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