Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Essential Roles for CD8+T Cells and Gamma Interferon in Protection of Mice against Retrovirus-Induced Immunosuppression

1 Jan 2002

Abstract excerpt

It is known that both animal and human retroviruses typically cause immunosuppression in their respective hosts, but the mechanisms by which this occurs are poorly understood. The present study uses Friend virus (FV) infections of mice as a model to determine how major histocompatibility complex (MHC) genes influence immunosuppression. Previously, MHC-I genes were shown to influence antibody responses to potent...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytomegalovirus and herpesvirus research
Share to Immunotherapy and Immune Responses
Share to T-cell and B-cell Immunology

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 11739713
DOI: 10.1128/jvi.76.1.450-454.2002

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Essential Roles for CD8+T Cells and Gamma Interferon in Protection of Mice against Retrovirus-Induced ImmunosuppressionPMID 11739713Read ↗

Immunity to retroviral infection: the Friend virus model.Semantic proximity Read ↗

Unique resistance of I/LnJ mice to a retrovirus is due to sustained interferon gamma-dependent production of virus-neutralizing antibodies.Semantic proximity Read ↗

Novel role of CD8(+) T cells and major histocompatibility complex class I genes in the generation of protective CD4(+) Th1 responses during retrovirus infection in mice.Semantic proximity Read ↗

Host genetic factors that control immune responses to retrovirus infections.Semantic proximity Read ↗

Critical Role for CD4+T Cells in Controlling Retrovirus Replication and Spread in Persistently Infected MiceSemantic proximity Read ↗

Nonredundant Roles of IL-10 and TGF-β in Suppression of Immune Responses to Hepatic AAV-Factor IX Gene TransferSemantic proximity Read ↗

Role of CD8 <sup>+</sup> T Cells in Control of West Nile Virus InfectionSemantic proximity Read ↗

Fv1 restriction and retrovirus vaccine immunity in Apobec3-deficient 129P2 mice.Semantic proximity Read ↗

Immunisation of Balb/c mice with severely attenuated murine cytomegalovirus mutants induces protective cellular and humoral immunity.Semantic proximity Read ↗

Targeted immunosuppression enhances repeated gene deliverySemantic proximity Read ↗

Inhibition of Interferons by Ectromelia VirusSemantic proximity Read ↗

A New In Vivo Model to Study Protective Immunity to Zika Virus Infection in Mice With Intact Type I Interferon SignalingSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.