Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Critical Role for CD4+T Cells in Controlling Retrovirus Replication and Spread in Persistently Infected Mice

1 Aug 1998

Abstract excerpt

Reactivations of persistent viral infections pose a significant medical problem in immunocompromised cancer, transplant, and AIDS patients, yet little is known about how persistent viral infections are immunologically controlled. Here we describe a mouse model for investigating the role of the immune response in controlling a persistent retroviral infection. We demonstrate that, following recovery from acute...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytomegalovirus and herpesvirus research
Share to HIV Research and Treatment
Share to Immune Cell Function and Interaction

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 9658100
DOI: 10.1128/jvi.72.8.6559-6564.1998

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Critical Role for CD4+T Cells in Controlling Retrovirus Replication and Spread in Persistently Infected MicePMID 9658100Read ↗

Establishment of a Novel Humanized Mouse Model To Investigate In Vivo Activation and Depletion of Patient-Derived HIV Latent ReservoirsSemantic proximity Read ↗

Efficacious control of cytomegalovirus infection after long-term depletion of CD8+ T lymphocytesSemantic proximity Read ↗

Immune determinants of pegivirus persistence, control, and cross-species infection in the laboratory mouseSemantic proximity Read ↗

Essential Roles for CD8+T Cells and Gamma Interferon in Protection of Mice against Retrovirus-Induced ImmunosuppressionSemantic proximity Read ↗

Within host RNA virus persistence: mechanisms and consequencesSemantic proximity Read ↗

T-cell heterogeneity, progenitor-progeny relationships, and function during latent and chronic viral infections.Semantic proximity Read ↗

Gammaherpesviruses and B Cells: A Relationship That Lasts a LifetimeSemantic proximity Read ↗

Progenitor and Terminal Subsets of CD8 <sup>+</sup> T Cells Cooperate to Contain Chronic Viral InfectionSemantic proximity Read ↗

CD8+ T Cells Prevent Lethality from Neonatal Murine Roseolovirus InfectionSemantic proximity Read ↗

A mature macrophage is a principal HIV-1 cellular reservoir in humanized mice after treatment with long acting antiretroviral therapySemantic proximity Read ↗

Immunity to retroviral infection: the Friend virus model.Semantic proximity Read ↗

Activation, control and T-bet+ B cell-mediated immune surveillance of endogenous retrovirusesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.