Meta-analysis of studies on genetic variation in 5-HT2A receptors and clozapine response.

doi:10.1016/s0920-9964(98)00032-2

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Article

Meta-analysis of studies on genetic variation in 5-HT2A receptors and clozapine response.

Schizophrenia research - 27 Jul 1998

Arranz M J, Munro J, Sham P, Kirov G, Murray R M, Collier D A, Kerwin R W

Abstract excerpt

Serotonin (5-HT) neurotransmitter receptors are targeted by atypical antipsychotic drugs. We hypothesized that genetic variation in these receptors may affect clinical response to the drugs targeting them. This hypothesis has been tested by several studies in which the correlation between polymor...

Topics

Alleles
Antipsychotic Agents
Clozapine
Genetic Variation
Genotype
Humans
Polymorphism, Genetic
Receptor, Serotonin, 5-HT2A
Receptors, Serotonin

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