Article
Association analysis of BMD-associated SNPs with knee osteoarthritis.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Jun 2014
Yerges-Armstrong Laura M, Yau Michelle S, Liu Youfang, Krishnan Subha, Renner Jordan B, Eaton Charles B, Kwoh C Kent, Nevitt Michael C, Duggan David J, Mitchell Braxton D, Jordan Joanne M, Hochberg Marc C, Jackson Rebecca D
Abstract excerpt
Osteoarthritis (OA) risk is widely recognized to be heritable but few loci have been identified. Observational studies have identified higher systemic bone mineral density (BMD) to be associated with an increased risk of radiographic knee osteoarthritis. With this in mind, we sought to evaluate whether well-established genetic loci for variance in BMD are associated with risk for radiographic OA in the...
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