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Article

Association between KLOTHO gene and hand osteoarthritis in a female Caucasian population.

Osteoarthritis and cartilage - 1 Jun 2007

Zhang F, Zhai G, Kato B S, Hart D J, Hunter D, Spector T D, Ahmadi K R

Abstract excerpt

OBJECTIVE: Osteoarthritis (OA) is a common complex disease with strong heritable components. In this study, we investigated the association between four putatively functional genetic variants in KLOTHO gene, a strong ageing-related gene, and hand OA in a large female Caucasian population. METHODS: Subjects (n=1015, age range 33-74 years) were selected from the TwinsUK Registry. Radiographs of both hands were...

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Identifiers

PMID: 17270470
DOI: 10.1016/j.joca.2006.12.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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