Article
The mouse Clock mutation behaves as an antimorph and maps within the W19H deletion, distal of Kit.
Genetics - 1 Jul 1997
King D P, Vitaterna M H, Chang A M, Dove W F, Pinto L H, Turek F W, Takahashi J S
Abstract excerpt
Clock is a semidominant mutation identified from an N-ethyl-N-nitrosourea mutagenesis screen in mice. Mice carrying the Clock mutation exhibit abnormalities of circadian behavior, including lengthening of endogenous period and loss of rhythmicity. To identify the gene affected by this mutation, we have generated a high-resolution genetic map (> 1800 meioses) of the Clock locus. We report that Clock is 0.7 cM...
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