Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of a rat model for usher syndrome type 1B by N-ethyl-N-nitrosourea mutagenesis-driven forward genetics.

Genetics - 1 Aug 2005

Smits Bart M G, Peters Theo A, Mul Joram D, Croes Huib J, Fransen Jack A M, Beynon Andy J, Guryev Victor, Plasterk Ronald H A, Cuppen Edwin

Abstract excerpt

The rat is the most extensively studied model organism and is broadly used in biomedical research. Current rat disease models are selected from existing strains and their number is thereby limited by the degree of naturally occurring variation or spontaneous mutations. We have used ENU mutagenesi...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosome Disorders
Share to Codon, Terminator
Share to Dyneins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Ethylnitrosourea

Share to Myosin VIIa

Share to Myosins

Share to Rats, Wistar

Share to Usher Syndromes

Source

Open in PubMed Open full text

Identifiers

PMID: 15965244
DOI: 10.1534/genetics.105.044222
PMCID: PMC1449770

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15965244-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of a rat model for usher syndrome type 1B by N-ethyl-N-nitrosourea mutagenesis-driven forward genetics.PMID 15965244Read ↗

ENU mutagenesis to generate genetically modified rat models.Semantic proximity Read ↗

Systematic generation of in vivo G protein-coupled receptor mutants in the rat.Semantic proximity Read ↗

ENU mutagenesis, a way forward to understand gene function.Semantic proximity Read ↗

Rat models of human diseases and related phenotypes: a systematic inventory of the causative genes.Semantic proximity Read ↗

Advances on genetic rat models of epilepsy.Semantic proximity Read ↗

Rat models of human diseases and related phenotypes: a systematic inventory of the causative genesSemantic proximity Read ↗

Rat models of human diseases and related phenotypes: a systematic inventory of the causative genesSemantic proximity Read ↗

Positional cloning of rat mutant genes reveals new functions of these genes.Semantic proximity Read ↗

Improved generation of rat gene knockouts by target-selected mutagenesis in mismatch repair-deficient animals.Semantic proximity Read ↗

Rat Models of Human Diseases and Related Phenotypes: A Novel Inventory of Causative Genes.Semantic proximity Read ↗

Zinc-finger nucleases: new strategies to target the rat genome.Semantic proximity Read ↗

Mouse ENU mutagenesis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.