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Apolipoprotein-E genotyping in Alzheimer's disease and frontotemporal dementia.

Dementia and geriatric cognitive disorders - 1 Jan 2000

Gustafson L, Abrahamson M, Grubb A, Nilsson K, Fex G

Abstract excerpt

Alzheimer's disease (AD) and frontotemporal dementia (FTD) are characterized by progressive neuronal loss and microvacuolization, although with different distributions of cortical involvement. In contrast to AD there is no amyloid, senile plaques or tangles in FTD. The involvement of chromosome 19 in AD has been associated with apoliprotein E (ApoE) and the epsilon 4 gene frequency has been related to increased...

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PMID: 9213069
DOI: 10.1159/000106637

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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