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Article

Apolipoprotein E polymorphism and Alzheimer's disease.

Lancet (London, England) - 18 Sept 1993

Poirier J, Davignon J, Bouthillier D, Kogan S, Bertrand P, Gauthier S

Abstract excerpt

Apolipoprotein E (apoE) is associated with Alzheimer's neurofibrillary tangles and beta-amyloid protein in senile plaques. It also appears to play an important part in the redistribution of lipids that follows deafferentation and neurodegeneration in the brain. The gene for apoE is on chromosome 19, within the genomic region previously associated with late-onset familial Alzheimer's disease (AD). We have studied...

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Identifiers

PMID: 8103819
DOI: 10.1016/0140-6736(93)91705-q

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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