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Article

Inherited defects of coagulation factor V: the hemorrhagic side.

Journal of thrombosis and haemostasis : JTH - 1 Jan 2006

Asselta R, Tenchini M L, Duga S

Abstract excerpt

Coagulation factor V (FV) is the protein cofactor required in vivo for the rapid generation of thrombin catalyzed by the prothrombinase complex. It also represents a central regulator in the early phases of blood clot formation, as it contributes to the anticoagulant pathway by participating in the downregulation of factor VIII activity. Conversion of precursor FV to either a procoagulant or anticoagulant...

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Identifiers

PMID: 16409445
DOI: 10.1111/j.1538-7836.2005.01590.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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