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Article

Coagulation factor V and thrombophilia: background and mechanisms.

Thrombosis and haemostasis - 1 Sept 2007

Segers Kenneth, Dahlbäck Björn, Nicolaes Gerry A F

Abstract excerpt

Human coagulation factor V (FV) is an essential coagulation protein with functions in both the pro- and anticoagulant pathways. Failure to express and control FV functions can either lead to bleeding, or to thromboembolic disease. Both events may develop into a life-threatening condition. Since the first description of APC resistance, and in particular the description of the so-called factor V(Leiden) mutation,...

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Source

Identifiers

PMID: 17849041

Genes

APC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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