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Article

Germline sequence variants of the LZTS1 gene are associated with prostate cancer risk.

Cancer genetics and cytogenetics - 1 Aug 2002

Hawkins Gregory A, Mychaleckyj Josyf C, Zheng Siqun L, Faith Dennis A, Kelly Brian, Isaacs S D, Wiley Kathleen E, Chang Bao-Li, Ewing Charles M, Bujnovszky Piroska, Bleecker Eugene R, Walsh P C, Meyers Deborah A, Isaacs William B, Xu Jianfeng

Abstract excerpt

The 8p22 through p23 region has been identified as a potential site for genes associated with prostate cancer. The gene LZTS1 has been mapped to the 8p22 through p23 region and identified as a potential tumor suppressor based on loss of heterozygosity studies using primary esophageal tumors. Sequence analysis of mRNA from various tumors has revealed multiple mutations and aberrant mRNA transcripts. The most...

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Identifiers

PMID: 12377406
DOI: 10.1016/s0165-4608(02)00549-6

Genes

LZTS1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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