Article
HU protein binding to the replication origin of the rolling-circle plasmid pKYM enhances DNA replication.
Molecular & general genetics : MGG - 20 May 1997
Yasukawa H, Ozaki E, Nakahama K, Masamune Y
Abstract excerpt
The RepK protein, which is encoded by the rolling-circle plasmid pKYM, binds to the PR I site in the pKYM DNA replication origin. We have identified HU as a protein that binds to the PR II and PR III sites in the replication-enhancing region which is downstream of PR I. DNA footprinting assays show that HU binds to these two sites only when RepK is bound to PR I, and that HU also enhances the binding of RepK to...
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