Article
Role of leader peptide synthesis in repZ gene expression of the ColIb-P9 plasmid.
The Journal of biological chemistry - 25 Jun 1990
Hama C, Takizawa T, Moriwaki H, Mizobuchi K
Abstract excerpt
The frequency of replication initiation of the ColIb-P9 plasmid depends on the level of repZ expression, which has been shown to be negatively regulated by inc RNA, the approximately 70-base-long product of the inc gene. To further understand the regulatory mechanism of repZ gene expression, we isolated mutants defective in ColIb-P9 replication using a lambda:ColIb-P9 hybrid phage. Among six mutants isolated, one...
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