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Article

Rep*: a viral element that can partially replace the origin of plasmid DNA synthesis of Epstein-Barr virus.

Journal of virology - 1 Jun 1998

Kirchmaier A L, Sugden B

Abstract excerpt

Replication of the Epstein-Barr viral (EBV) genome occurs once per cell cycle during latent infection. Similarly, plasmids containing EBV's plasmid origin of replication, oriP, are replicated once per cell cycle. Replication from oriP requires EBV nuclear antigen 1 (EBNA-1) in trans; however, its contributions to this replication are unknown. oriP contains 24 EBNA-1 binding sites; 20 are located within the family...

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Identifiers

PMID: 9573229
DOI: 10.1128/JVI.72.6.4657-4666.1998
PMCID: PMC109986

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Research trail→

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Rep*: a viral element that can partially replace the origin of plasmid DNA synthesis of Epstein-Barr virus.PMID 9573229Read ↗

Initiation of DNA replication within oriP is dispensable for stable replication of the latent Epstein-Barr virus chromosome after infection of established cell lines.Semantic proximity Read ↗

Plasmid maintenance of derivatives of oriP of Epstein-Barr virusSemantic proximity Read ↗

Epstein-Barr virus-derived plasmids replicate only once per cell cycle and are not amplified after entry into cellsSemantic proximity Read ↗

Sequence requirements of the Epstein-Barr virus latent origin of DNA replicationSemantic proximity Read ↗

The minimal replicator of Epstein-Barr virus oriP.Semantic proximity Read ↗

Establishment of an <i>oriP</i> Replicon Is Dependent upon an Infrequent, Epigenetic EventSemantic proximity Read ↗

The plasmid replicon of Epstein–Barr virus: Mechanistic insights into efficient, licensed, extrachromosomal replication in human cellsSemantic proximity Read ↗

Telomere Repeat Binding Factors TRF1, TRF2, and hRAP1 Modulate Replication of Epstein-Barr Virus OriPSemantic proximity Read ↗

The Linking Regions of EBNA1 Are Essential for Its Support of Replication and TranscriptionSemantic proximity Read ↗

EBNA1 can link the enhancer element to the initiator element of the Epstein-Barr virus plasmid origin of DNA replicationSemantic proximity Read ↗

Genetic evidence that EBNA-1 is needed for efficient, stable latent infection by Epstein-Barr virus.Semantic proximity Read ↗

Essential Role of Rta in Lytic DNA Replication of Epstein-Barr VirusSemantic proximity Read ↗

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