Rep*: a viral element that can partially replace the origin of plasmid DNA synthesis of Epstein-Barr virus.

doi:10.1128/JVI.72.6.4657-4666.1998

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Article

Rep*: a viral element that can partially replace the origin of plasmid DNA synthesis of Epstein-Barr virus.

Journal of virology - 1 Jun 1998

Kirchmaier A L, Sugden B

Abstract excerpt

Replication of the Epstein-Barr viral (EBV) genome occurs once per cell cycle during latent infection. Similarly, plasmids containing EBV's plasmid origin of replication, oriP, are replicated once per cell cycle. Replication from oriP requires EBV nuclear antigen 1 (EBNA-1) in trans; however, its...

Topics

Cell Line
DNA Helicases
DNA Replication
DNA, Viral
DNA-Binding Proteins
Genome, Viral
Herpesvirus 4, Human
Humans
Mutation
Plasmids
Trans-Activators
Viral Proteins

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