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Article

UvrD-dependent replication of rolling-circle plasmids in Escherichia coli.

Molecular microbiology - 1 Jan 2000

Bruand C, Ehrlich S D

Abstract excerpt

The Escherichia coli UvrD helicase (or helicase II) is known for its involvement in DNA repair. We report that UvrD is required for DNA replication of several different rolling-circle plasmids in E. coli, whereas its homologue, the Rep helicase, is not. Lack of UvrD helicase does not impair the first step of plasmid replication, nicking of the double-stranded origin by the plasmid initiator protein. However,...

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Identifiers

PMID: 10632890
DOI: 10.1046/j.1365-2958.2000.01700.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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