Article
Debrisoquine metabolism and lung cancer risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jan 2000
Shaw G L, Falk R T, Deslauriers J, Frame J N, Nesbitt J C, Pass H I, Issaq H J, Hoover R N, Tucker M A
Abstract excerpt
Previous reports of the association between the debrisoquine metabolic polymorphism and lung cancer risk have been conflicting. We examined the hypothesis that the genetically determined ability to metabolize debrisoquine identifies individuals at increased risk for lung cancer in a study designe...
Topics
- Aged
- Biomarkers, Tumor
- Case-Control Studies
- Confounding Factors, Epidemiologic
- Debrisoquin
- Disease Susceptibility
- Female
- Humans
- Logistic Models
- Lung Neoplasms
- Male
- Maryland
- Middle Aged
- Neoplasm Staging
- Phenotype
- Polymorphism, Genetic
- Quebec
- Risk Factors