Article
Mutant bacteriophage T7 RNA polymerases with altered termination properties.
Journal of molecular biology - 30 May 1997
Lyakhov D L, He B, Zhang X, Studier F W, Dunn J J, McAllister W T
Abstract excerpt
We have identified mutants of bacteriophage T7 RNA polymerase (RNAP) that are altered in their ability to pause or terminate at a variety of signals. These signals include a terminator found fortuitously in the human preproparathyroid hormone (PTH) gene, a pause site found in the concatamer junction (CJ) of replicating T7 DNA, and termination signals that are also utilized by Escherichia coli RNAP (e.g. rrnB T1...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
