Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Termination and slippage by bacteriophage T7 RNA polymerase.

Journal of molecular biology - 20 Aug 1993

Macdonald L E, Zhou Y, McAllister W T

Abstract excerpt

We have examined the termination efficiency of T7 and T3 RNA polymerases (RNAPs) at a variety of termination signals. In agreement with previous investigators we find that termination occurs after the synthesis of an RNA product with a stable secondary structure followed by a run of U residues. Stem-loop structures that lack a 3' U-tract fail to terminate the phage enzyme. The distance (or the sequence) between...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to DNA, Bacterial
Share to DNA, Viral

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Models, Genetic

Share to Molecular Sequence Data

Share to Mutation

Share to Nucleic Acid Conformation

Share to Repetitive Sequences, Nucleic Acid

Source

Identifiers

PMID: 8371265
DOI: 10.1006/jmbi.1993.1458

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Termination and slippage by bacteriophage T7 RNA polymerase.PMID 8371265Read ↗

Mutant bacteriophage T7 RNA polymerases with altered termination properties.Semantic proximity Read ↗

A single mutation attenuates both the transcription termination and RNA-dependent RNA polymerase activity of T7 RNA polymerase.Semantic proximity Read ↗

Recent advances in understanding transcription termination by RNA polymerase IISemantic proximity Read ↗

Transcription termination at intrinsic terminators: the role of the RNA hairpin.Semantic proximity Read ↗

RNA sequence and structure determinants of Pol III transcriptional termination in human cellsSemantic proximity Read ↗

Human RNA polymerase III termination favors decomposition over facilitated recycling.Semantic proximity Read ↗

Unraveling the mechanistic features of RNA polymerase II termination by the 5'-3' exoribonuclease Rat1.Semantic proximity Read ↗

Probing conformational changes in T7 RNA polymerase during initiation and termination by using engineered disulfide linkages.Semantic proximity Read ↗

Nonpolyadenylated RNA polymerase II termination is induced by transcript cleavage.Semantic proximity Read ↗

Role of the non-template strand of the elongation bubble in intrinsic transcription termination.Semantic proximity Read ↗

Determination of intrinsic transcription termination efficiency by RNA polymerase elongation rate.Semantic proximity Read ↗

A mutant T7 RNA polymerase that is defective in RNA binding and blocked in the early stages of transcription.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.