Article
Lack of beta-catenin affects mouse development at gastrulation.
Development (Cambridge, England) - 1 Nov 1995
Haegel H, Larue L, Ohsugi M, Fedorov L, Herrenknecht K, Kemler R
Abstract excerpt
Molecular analysis of the cadherin-catenin complex elucidated the central role of beta-catenin in this adhesion complex, as it binds to the cytoplasmic domain of E-cadherin and to alpha-catenin. beta-Catenin may also function in signalling pathways, given its homology to the gene product of the D...
Topics
- Animals
- Base Sequence
- Cadherins
- Cell Adhesion
- Cytoskeletal Proteins
- Ectoderm
- Gastrula
- Gene Targeting
- In Situ Hybridization
- Mice
- Mice, Knockout
- Molecular Sequence Data
- Morphogenesis
- Phenotype
- Polymerase Chain Reaction
- Trans-Activators
- beta Catenin