T cell receptor Ddelta2Ddelta3 rearrangement: a suitable allele-specific marker for the detection of minimal residual disease in childhood acute lymphoblastic leukemia.

doi:10.1038/sj.leu.2400643

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Article

T cell receptor Ddelta2Ddelta3 rearrangement: a suitable allele-specific marker for the detection of minimal residual disease in childhood acute lymphoblastic leukemia.

Leukemia - 1 May 1997

Seriu T, Erz D, Stark Y, Bartram C R

Abstract excerpt

The applicability of T cell receptor (TCR) Ddelta2Ddelta3 junctional regions for the detection of minimal residual disease (MRD) was examined in childhood acute lymphoblastic leukemia (ALL). Southern blot analysis showed a Ddelta2Ddelta3 rearrangement in 22 of 172 (13%) precursor-B ALL. No Ddelta...

Topics

Alleles
Base Sequence
Bone Marrow
Child
DNA Primers
DNA Probes
DNA Transposable Elements
Gene Rearrangement, delta-Chain T-Cell Antigen Receptor
Genetic Markers
Genetic Variation
Humans
Polymerase Chain Reaction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Precursor Cell Lymphoblastic Leukemia-Lymphoma

Prognosis

Receptors, Antigen, T-Cell, gamma-delta

Recombination, Genetic

Sensitivity and Specificity

Sequence Deletion

Source

Open in PubMed

Identifiers

PMID: 9180303
DOI: 10.1038/sj.leu.2400643

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9180303-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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