Applicability of IG/TCR gene rearrangements as targets for minimal residual disease assessment in a population-based cohort of Swedish childhood acute lymphoblastic leukaemia diagnosed 2002-2006.

doi:10.1111/j.1600-0609.2009.01374.x

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Article

Applicability of IG/TCR gene rearrangements as targets for minimal residual disease assessment in a population-based cohort of Swedish childhood acute lymphoblastic leukaemia diagnosed 2002-2006.

European journal of haematology - 1 Feb 2010

Thörn Ingrid, Forestier Erik, Thuresson Britt, Wasslavik Carina, Malec Maria, Li Aihong, Lindström-Eriksson Elenor, Botling Johan, Barbany Gisela, Jacobsson Stefan, Olofsson Tor, Porwit Anna, Sundström Christer, Rosenquist Richard

Abstract excerpt

Minimal residual disease (MRD) detection during the early treatment phase has become an important stratification parameter in many childhood acute lymphoblastic leukaemia (ALL) treatment protocols. Here, we aimed to address the applicability of rearranged antigen-receptor genes as potential MRD markers using real-time quantitative polymerase chain reaction (RQ-PCR) in a Swedish population-based cohort. From 334...

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PMID: 19895569
DOI: 10.1111/j.1600-0609.2009.01374.x

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