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Article

A function in apoptosis other than transactivation inherent in the NH2-terminal domain of p53.

International journal of cancer - 29 May 1997

Theis S, Atz J, Mueller-Lantzsch N, Roemer K

Abstract excerpt

p53-mediated programmed cell death (PMCD) often requires an intact transactivation domain of the p53 tumor suppressor and is therefore usually interpreted to rely upon the transactivation of genes. As a notable exception, murine GHFT1 cells have been documented to perish in a p53-dependent manner even in the presence of transcription inhibitor actinomycin D (Act D) and have since served as one model system for...

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Identifiers

PMID: 9180157
DOI: 10.1002/(sici)1097-0215(19970529)71:5<858::aid-ijc26>3.0.co;2-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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