Lack of association of cytochrome P450 2E1 genetic polymorphisms with the risk of human hepatocellular carcinoma.

doi:10.1002/(sici)1097-0215(19970529)71:5<737::aid-ijc8>3.0.co;2-s

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Article

Lack of association of cytochrome P450 2E1 genetic polymorphisms with the risk of human hepatocellular carcinoma.

International journal of cancer - 29 May 1997

Lee H S, Yoon J H, Kamimura S, Iwata K, Watanabe H, Kim C Y

Abstract excerpt

The iso-enzyme pattern of cytochrome P450 was shown to be related to the development of chemically induced hepatocellular carcinoma (HCC) in rats, which is accelerated by chronic alcohol ingestion. Our study was designed to investigate the association of cytochrome P450 2E1 (CYP2E1) genetic polym...

Topics

Alcohol Drinking
Alleles
Carcinoma, Hepatocellular
Cytochrome P-450 CYP2E1
Gene Frequency
Genotype
Humans
Japan
Korea
Liver Neoplasms
Polymorphism, Restriction Fragment Length
Risk Factors

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