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Article

Lack of association of cytochrome P450 2E1 genetic polymorphisms with the risk of human hepatocellular carcinoma.

International journal of cancer - 29 May 1997

Lee H S, Yoon J H, Kamimura S, Iwata K, Watanabe H, Kim C Y

Abstract excerpt

The iso-enzyme pattern of cytochrome P450 was shown to be related to the development of chemically induced hepatocellular carcinoma (HCC) in rats, which is accelerated by chronic alcohol ingestion. Our study was designed to investigate the association of cytochrome P450 2E1 (CYP2E1) genetic polymorphisms with the susceptibility to HCC in humans with and without chronic alcohol ingestion. We enrolled 171 male...

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Identifiers

PMID: 9180139
DOI: 10.1002/(sici)1097-0215(19970529)71:5<737::aid-ijc8>3.0.co;2-s

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Source receipt: pubmed, retrieved 7 Sept 2026.

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