Cytochrome P450 2E1 and glutathione S-transferase M1 polymorphisms and susceptibility to hepatocellular carcinoma.

doi:10.1016/0016-5085(95)90587-1

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Article

Cytochrome P450 2E1 and glutathione S-transferase M1 polymorphisms and susceptibility to hepatocellular carcinoma.

Gastroenterology - 1 Oct 1995

Yu M W, Gladek-Yarborough A, Chiamprasert S, Santella R M, Liaw Y F, Chen C J

Abstract excerpt

BACKGROUND & AIMS: Genetic polymorphisms in enzymes involved in carcinogen metabolism have been found to influence susceptibility to cancer. The aim of this study was to examine whether cytochrome P450 2E1 (CYP2E1) and/or glutathione S-transferase M1 (GSTM1) genetic polymorphisms were related to...

Topics

Adult
Aged
Alcohol Drinking
Base Sequence
Carcinoma, Hepatocellular
Case-Control Studies
Cohort Studies
Cytochrome P-450 CYP2E1
Cytochrome P-450 Enzyme System
Disease Susceptibility
Genotype
Glutathione Transferase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Liver Neoplasms

Male

Middle Aged

Molecular Sequence Data

Oxidoreductases, N-Demethylating

Source

Open in PubMed

Identifiers

PMID: 7557094
DOI: 10.1016/0016-5085(95)90587-1

Genes

GSTM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7557094-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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