Article
Genetic polymorphisms of ALDH2 and ADH2 are not associated with risk of hepatocellular carcinoma among East Asians.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Jun 2012
Zhou Daming, Xiao Li, Zhang Yun, Xian Jianchun, Jiang Jijun, Zong Wenhong, Huang Zuxuan, Yang Yongfeng
Abstract excerpt
The aldehyde dehydrogenase 2 (ALDH2) and alcohol dehydrogenase 2 (ADH2) genes have been implicated in the development of hepatocellular carcinoma (HCC). However, the results have been inconsistent. In this study, we performed a meta-analysis to clarify the associations between polymorphisms of ALDH2 and ADH2 genes and HCC. Published literatures from PubMed and Embase were retrieved. Pooled odds ratio (OR) with...
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