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Article

Cytochrome P4502E1 (CYP2E1) genetic polymorphism in a case-control study of gastric cancer and liver disease.

Pharmacogenetics - 1 Jan 1995

Kato S, Onda M, Matsukura N, Tokunaga A, Tajiri T, Kim D Y, Tsuruta H, Matsuda N, Yamashita K, Shields P G

Abstract excerpt

Cytochrome P4502E1 (CYP2E1) activates carcinogenic N-nitrosamines, benzene, urethane and other low molecular weight compounds. This enzyme is also inducible by ethanol, and metabolizes alcohol. A restriction fragment length polymorphism (RFLP) using the Rsa I restriction enzyme has been identified in the CYP2E1 transcription regulatory region; recent studies suggest that this polymorphism may affect gene...

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PMID: 7581484
DOI: 10.1097/00008571-199512001-00016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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