Article
The missing ApoE allele.
Annals of human genetics - 1 Jul 2007
Seripa D, Matera M G, Daniele A, Bizzarro A, Rinaldi M, Gravina C, Bisceglia L, Corbo R M, Panza F, Solfrizzi V, Fazio V M, Forno G Dal, Masullo C, Dallapiccola B, Pilotto A
Abstract excerpt
The human apoE gene (APOE, GenBank accession AF261279) shows a common polymorphism, with the three epsilon2, epsilon3 and epsilon4 alleles resulting from the haplotypes of two C-->T SNPs. However, whereas the three common T-T, T-C and C-C haplotypes corresponding to the epsilon2, epsilon3 and epsilon4 alleles are well known, the last C-T haplotype (GenBank accession AY077451), encoding a fourth apoE allele, has...
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