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Mechanism of Ca2+ release at fertilization in mammals

15 Oct 1999

Abstract excerpt

At fertilization in mammals the sperm triggers a series of oscillations in intracellular Ca2+ within the egg. These Ca2+ oscillations activate the development of the egg into an embryo. It is not known how the sperm triggers these Ca2+ oscillations. There are currently three different theories for Ca2+ signaling in eggs at fertilization. One idea is that the sperm acts as a conduit for Ca2+ entry into the egg...

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Identifiers

PMID: 10497326
DOI: 10.1002/(sici)1097-010x(19991015)285:3<267::aid-jez10>3.0.co;2-p

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