Article
Genetic modifiers of Leprfa associated with variability in insulin production and susceptibility to NIDDM.
Genomics - 1 May 1997
Chung W K, Zheng M, Chua M, Kershaw E, Power-Kehoe L, Tsuji M, Wu-Peng X S, Williams J, Chua S C, Leibel R L
Abstract excerpt
In an attempt to identify the genetic basis for susceptibility to non-insulin-dependent diabetes mellitus within the context of obesity, we generated 401 genetically obese Leprfa/Leprfa F2 WKY13M intercross rats that demonstrated wide variation in multiple phenotypic measures related to diabetes,...
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