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Article

A single residue polymorphism at DR beta 37 affects recognition of peptides by T cells.

Human immunology - 15 Apr 1997

Chen Y Z, Matsushita S, Nishimura Y

Abstract excerpt

Single amino acid polymorphism at residue 37 of the HLA-DR beta chain (DR beta 37) between DRB1*0406 and 0403 markedly influences susceptibility to the insulin autoimmune syndrome. We investigated the effects of DR beta 37 polymorphism regarding recognition of nonself peptides by a T-cell clone, YN5-32, specific to a streptococcal peptide (M12p54-68) presented by the DRB1*0406 molecule. YN5-32 responded better to...

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PMID: 9154455
DOI: 10.1016/s0198-8859(97)00013-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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