Article
Effects of neuroamines and divalent cations on cloned and mutated ATP-gated channels.
European journal of pharmacology - 23 Apr 1997
Nakazawa K, Ohno Y
Abstract excerpt
Sensitivities to dopamine, 5-hydroxytryptamine, Zn2+ and Cd2+ were studied in P2X1, P2X2, P2X3 and P2X4 purinoceptors and mutants of P2X2 purinoceptors expressed in Xenopus oocytes. Dopamine (10 and 100 microM) and 5-hydroxytryptamine (1 to 100 microM) enhanced the inward current activated by extracellular ATP through P2X2 and P2X4 purinoceptors. Zn2+ (1 to 100 microM) and Cd2+ (10 microM to 1 microM) enhanced...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
