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Article

Heteromultimeric P2X(1/2) receptors show a novel sensitivity to extracellular pH.

The Journal of pharmacology and experimental therapeutics - 1 Feb 2002

Brown Sean G, Townsend-Nicholson Andrea, Jacobson Kenneth A, Burnstock Geoffrey, King Brian F

Abstract excerpt

Rat P2X(1) and P2X(2) subunits were coexpressed in defolliculated Xenopus oocytes and the resultant P2X receptors studied under voltage-clamp conditions. Extracellular ATP elicited biphasic inward currents, involving an initial rapidly inactivating (P2X(1)-like) component and a later slowly inact...

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Identifiers

PMID: 11805232
DOI: 10.1124/jpet.300.2.673
PMCID: PMC5577565

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-11805232-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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