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Article

Allosteric modulation of ATP-gated P2X receptor channels.

Reviews in the neurosciences - 1 Jan 2011

Coddou Claudio, Stojilkovic Stanko S, Huidobro-Toro J Pablo

Abstract excerpt

Seven mammalian purinergic receptor subunits, denoted P2X1-P2X7, and several spliced forms of these subunits have been cloned. When heterologously expressed, these cDNAs encode ATP-gated non-selective cation channels organized as trimers. All activated receptors produce cell depolarization and promote Ca(2+) influx through their pores and indirectly by activating voltage-gated calcium channels. However, the...

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Identifiers

PMID: 21639805
DOI: 10.1515/RNS.2011.014
PMCID: PMC3647606

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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