Article
Changes in osteopontin mRNA expression during phenotypic transition of rabbit arterial smooth muscle cells.
Histochemistry and cell biology - 1 Apr 1997
Yamamoto M, Aoyagi M, Azuma H, Yamamoto K
Abstract excerpt
Transition from a contractile to a synthetic phenotype appears to be an early key event during the development of intimal thickening after arterial wall injury. We examined the expression of osteopontin mRNA, proliferation, and phenotypic properties of smooth muscle cells (SMCs) in rabbit neointima after balloon denudation and in primary culture. A strong osteopontin mRNA signal was detected in the thickened...
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