Article
Resting smooth muscle cells as a model for studying vascular cell activation.
Tissue & cell - 1 Apr 2006
Poliseno Laura, Cecchettini Antonella, Mariani Laura, Evangelista Monica, Ricci Fernanda, Giorgi Franco, Citti Lorenzo, Rainaldi Giuseppe
Abstract excerpt
Vascular smooth muscle (VSM) cells constitute the main structural components of tunica media. Under physiological conditions, these cells display a contractile phenotype and a low proliferative activity. However, they may also acquire a synthetic phenotype and become predominantly proliferative if stimulated under certain stress conditions. This capacity plays a major role in the inception and progression of such...
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