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Article

A four-amino-acid insertion in the ligand-binding domain inactivates hRXRbeta and renders dominant negative activity.

DNA and cell biology - 1 Apr 1997

Mahajna J, Shi B, Bruskin A

Abstract excerpt

Retinoid X receptors (RXRs) are members of the steroid and thyroid hormone receptor superfamily of hormone-dependent transcription factors that mediate the pleiotropic effect of retinoids. Here, we report the initial characterization of an isoform of hRXR beta, termed hRXR beta3, which was previously identified as an H-2RIIBP isoform (Epplen and Epplen, 1992). The hRXR beta3 isoform cotains an in-frame insertion...

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Identifiers

PMID: 9150434
DOI: 10.1089/dna.1997.16.463

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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