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Article

Dominant negative retinoic acid receptor beta.

Mechanisms of development - 1 Mar 1993

Shen S, van der Saag P T, Kruijer W

Abstract excerpt

Induction of the retinoic acid receptor beta 2 (RAR beta 2) gene by retinoic acid (RA) is mediated by a RA response element (RARE), which represents a high affinity binding site for RAR/RXR heterodimers acting at this site as RA-inducible transcription activators. In RA resistant RAC65 cells, RAR...

Topics

Amino Acid Sequence
Base Sequence
Carrier Proteins
Genes, Dominant
Molecular Sequence Data
Mutation
Promoter Regions, Genetic
Receptors, Cell Surface
Receptors, Retinoic Acid
Regulatory Sequences, Nucleic Acid
Repressor Proteins
Retinoid X Receptors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Transcription Factors

Transcriptional Activation

Tretinoin

Tumor Cells, Cultured

Source

Identifiers

PMID: 8388240
DOI: 10.1016/0925-4773(93)90075-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8388240-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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